Proliferating cell nuclear antigen in hepatocellular carcinoma and small cell liver dysplasia
نویسندگان
چکیده
منابع مشابه
Proliferating cell nuclear antigen (PCNA) activity in hepatocellular carcinoma, benign peri-neoplastic and normal liver.
Hepatocellular carcinoma (HCC) is among the ten most common cancers in Malaysian males. As cellular proliferation is an important feature of malignant transformation, we studied the proliferation pattern of normal and benign perineoplastic liver versus hepatocellular carcinoma in an attempt to further understand the tumour transformation process. 39 HCC (21 with accompanying and 18 without cirr...
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Proliferating cell nuclear antigen (PCNA) is an auxiliary protein of DNA • @polymerase-• Ý • @ that • @is • @ synthesized • @ during • @ the • @ late • @G1 • @ phase through the S phase of cell proliferation. The expression of PCNA correlates strongly with cell proliferation. In the present study, employing NC-012, which is an anti-human PCNA monoclonal antibody, we performed immunohistochemica...
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ژورنال
عنوان ژورنال: Cancer
سال: 1993
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19931115)72:10<2902::aid-cncr2820721008>3.0.co;2-2